Iron-deficiency anemia

Iron-deficiency anemia

  • Inadequate dietary intake
    • 5% to 10% of ingested iron is absorbed
  • Malabsorption
    • Iron absorption occurs in the duodenum
    • Diseases or surgery that alter, destroy, or remove absorption surface of this area of intestine cause anemia
  • Blood loss
    • 2 mL whole blood contain 1 mg iron
    • Major cause of iron deficiency in adults
    • Chronic blood loss most commonly through GI and GU systems
  • Hemolysis
  • Pregnancy contributes to this condition
  • At-risk groups
    • Premenopausal women
    • Pregnant women
    • Persons from low socioeconomic backgrounds
    • Older adults
    • Individuals experiencing blood loss

Clinical manifestations

  • General manifestations of anemia
    • Pallor is most common
    • Glossitis is second
      • Inflammation of tongue
    • Cheilitis is also found
      • Inflammation of lips

Diagnostic studies

  • Laboratory findings
    • Hgb, Hct, MCV, MCH, MCHC, reticulocytes, serum iron, TIBC, bilirubin, platelets
  • Stool occult blood test
  • Endoscopy
  • Colonoscopy

Interprofessional care

  • Goal
    • Treat underlying disease causing reduced intake or absorption of iron
  • Replace iron
    • Nutritional therapy
    • Oral iron supplements
    • Transfusion of packed RBCs

Drug therapy

  • Parenteral iron
    • Indicated for malabsorption, oral iron intolerance, need for iron beyond normal limits, poor patient compliance
    • Can be given IM or IV
    • IM may stain skin
      • Z-track

Share:

More Posts

Fibromyalgia

Print KEY POINTS Fibromyalgia causes pain, fatigue, emotional and mental distress, and sleep problems. There is no cure, but you can manage it with self-care,

Chickenpox (Varicella)

For Everyone About Chickenpox KEY POINTS Chickenpox is a highly contagious disease caused by the varicella-zoster virus (VZV). The virus spreads mainly through close contact

Managing High Blood Pressure

For Everyone KEY POINTS Measuring your blood pressure is an important step toward controlling high blood pressure. If you have diabetes, you may also have