Iron-deficiency anemia

Iron-deficiency anemia

  • Inadequate dietary intake
    • 5% to 10% of ingested iron is absorbed
  • Malabsorption
    • Iron absorption occurs in the duodenum
    • Diseases or surgery that alter, destroy, or remove absorption surface of this area of intestine cause anemia
  • Blood loss
    • 2 mL whole blood contain 1 mg iron
    • Major cause of iron deficiency in adults
    • Chronic blood loss most commonly through GI and GU systems
  • Hemolysis
  • Pregnancy contributes to this condition
  • At-risk groups
    • Premenopausal women
    • Pregnant women
    • Persons from low socioeconomic backgrounds
    • Older adults
    • Individuals experiencing blood loss

Clinical manifestations

  • General manifestations of anemia
    • Pallor is most common
    • Glossitis is second
      • Inflammation of tongue
    • Cheilitis is also found
      • Inflammation of lips

Diagnostic studies

  • Laboratory findings
    • Hgb, Hct, MCV, MCH, MCHC, reticulocytes, serum iron, TIBC, bilirubin, platelets
  • Stool occult blood test
  • Endoscopy
  • Colonoscopy

Interprofessional care

  • Goal
    • Treat underlying disease causing reduced intake or absorption of iron
  • Replace iron
    • Nutritional therapy
    • Oral iron supplements
    • Transfusion of packed RBCs

Drug therapy

  • Parenteral iron
    • Indicated for malabsorption, oral iron intolerance, need for iron beyond normal limits, poor patient compliance
    • Can be given IM or IV
    • IM may stain skin
      • Z-track

Share:

More Posts

Cold Versus Flu

For Everyone AUG. 8, 2024 ESPAÑOL PURPOSE Influenza (flu) and the common cold are both contagious respiratory illnesses, but they are caused by different viruses.

Ebola Disease Basics

For Everyone JUNE 2, 2026 ESPAÑOL KEY POINTS Ebola disease is caused by an infection with an orthoebolavirus. Orthoebolaviruses are found primarily in sub-Saharan Africa.

What Is Angina?

Español Angina can be a warning sign that you are at a higher risk of having a heart attack. If you have chest pain that

About Swimmer’s Itch

For Everyone KEY POINTS Swimmer’s itch is an infection caused by a parasite. It can cause an allergic reaction and rash on your skin. Swimmer’s