Role of immune system

Role of immune system

  • Immune response is to reject or destroy cancer cells
    • May be inadequate as cancer cells arise from normal human cells
  • Some cancer cells have changes on their surface antigens
    • Tumor-associated antigens (TAAs)
  • Cytotoxic  T cells
    • Kill tumor cells directly
    • Produce cytokines
  • Natural killer cells and activated macrophages can lyse tumor cells
  • B cells produce antibodies that bind to tumor cells


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