Nursing and Interprofessional management : Anemia Sickle Cell Disease

Nursing and Interprofessional management

  • Care is directed toward
    • Prevention of sequelae from disease
    • Alleviating manifestations from complications
    • Minimizing end-organ damage
    • Promptly treating serious sequelae
  • Hospitalized patients in sickle cell crisis
    • O2 for hypoxia and to control sickling
    • Vigilance for respiratory failure
    • Rest with DVT prophylaxis
    • Administration of fluids and electrolytes
    • Transfusion therapy
      • Chelation therapy with repeat exacerbations
  • Under-treatment is a major problem
  • Pain management
    • Often pain medication tolerant
    • Require continuous and breakthrough analgesia with morphine and hydromorphone
    • Multimodal and interdisciplinary approach involving emotional and adjunctive measures
  • Treat infections
  • Administer folic acid
  • Hydrea is only antisickling agent shown to be clinically beneficial
  • Hematopoietic stem cell transplantation (HSCT) is only available cure
  • Patient and caregiver teaching and support are important
    • How to avoid crises
    • Importance of prompt medical attention
    • Pain control

Patient education

  • Avoidance of high altitudes
  • Maintenance of adequate fluid intake
  • Proper treatment of infections
  • Immunizations for pneumonia, Haemophilus influenzae, influenza, and hepatitis should be given.
  • Direct patient to seek medical attention quickly when symptoms return.


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