|Intracranial Pressure||May result from radiation edema in central nervous system.||Monitor neurologic status.|
May be controlled with corticosteroids.
|Peripheral Neuropathy||Paresthesias, arelexia, skeletal muscle weakness, and smooth muscle dysfunction can occur as a side effect of plant alkaloids, taxanes, and cisplatin||Monitor for these manifestations in patients on these drugs.|
Consider temporary chemotherapy dose interruption or reduction until symptoms improve.
Anti-seizure drugs (e.g., gabapentin [Neurontin]) may be considered.
|Cognitive Changes (“chemo brain”)||Occur during and after treatment (especially with chemotherapy).|
Difficulties in concentration, memory lapses, trouble remembering details, taking longer to finish tasks.
May happen quickly and last a short time. Sometimes people have mild long-term effects
|Teach patients to do the following:|
Use detailed daily planner.
Get enough sleep and rest.
Exercise brain (learn something new, do word puzzles).
Focus on one thing (no multi-tasking)