Inflammation : Vascular response

Inflammation

  • Sequential response to cell injury that:
    • Neutralizes and dilutes inflammatory agent
    • Removes necrotic materials
    • Establishes an environment suitable for healing and repair
  • Inflammatory response can be divided into
    • Vascular response
    • Cellular response
    • Formation of exudate
    • Healing

Vascular response

  • After cell injury, arterioles in area briefly undergo transient vasoconstriction
  • After release of histamine and other chemicals by injured cells, vessels dilate, resulting in hyperemia
  • Vasodilation chemical mediators
    • Increased capillary permeability
    • Movement of fluid from capillaries into tissue spaces
  • Fluid in tissue spaces
    • Initially composed of serous fluid
    • Later contains plasma proteins, primarily albumin
      • Proteins exert oncotic pressure that further draws fluid from blood vessels
      • Tissue becomes edematous
  • As plasma protein fibrinogen leaves blood, it is activated to fibrin by products of injured cells
  • Fibrin strengthens blood clot formed by platelets
  • In tissues, clot traps bacteria to prevent spread

Share:

More Posts

The Power of Pets

Health Benefits of Human-Animal Interactions En españolSend us your comments(link sends e-mail) Nothing compares to the joy of coming home to a loyal companion. The

Sports Injuries

Overview of Sports Injuries The term “sports injury” refers to the kinds of injuries that most commonly occur during sports or exercise, but they are not

Emergency Services Houston

Urgent Care for Kids

Urgent care centers are a great option for treating sick or injured children. They offer family-friendly care and can treat a wide variety of conditions,

Seasonal Allergies at a Glance

If you have an allergy, your immune system reacts to something that doesn’t bother most other people. People with seasonal allergies (also called hay fever