Complications

Miliary TB
- Large numbers of organisms spread via the bloodstream to distant organs
- Fatal if untreated
- Manifestations progress slowly and vary depending on which organs are infected
- Fever, cough, and lymphadenopathy occur
- Can include hepatomegaly and splenomegaly
Pleural TB
- Chest pain, fever, cough, and a unilateral pleural effusion are common
- Pleural effusion
  - Bacteria in pleural space cause inflammation.
  - Pleural exudates of protein-rich fluid
- Empyema
  - Large numbers of tubercular organisms in pleural space
TB pneumonia
- Large amounts of bacilli discharged from granulomas into lung or lymph nodes
- Manifests as bacterial pneumonia
Other organ development
- Spinal destruction
- Bacterial meningitis
- Peritonitis

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